KCNQ1OT1 promotes the proliferation and migration of psoriatic keratinocytes by regulating miR-183-3p/GAB1 | Zendy

Ting Liu | Zendy; Xi Duan | Zendy; Jia He | Zendy; Chuan Yang | Zendy

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KCNQ1OT1 promotes the proliferation and migration of psoriatic keratinocytes by regulating miR-183-3p/GAB1

Author(s) -

Ting Liu,

Xi Duan,

Jia He,

Chuan Yang

Publication year - 2021

Publication title -

allergologia et immunopathologia

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.483

H-Index - 37

eISSN - 1578-1267

pISSN - 0301-0546

DOI - 10.15586/aei.v49i5.480

Subject(s) - hacat , viability assay , cancer research , cell growth , medicine , gene knockdown , microrna , microbiology and biotechnology , cell migration , keratinocyte , cell culture , biology , genetics , gene

Differentially expressed long non-coding RNAs (lncRNA) have been reported to be involved in the proliferation and migration of keratinocyte. Potassium voltage-gated channel subfamily Q member 1 overlapping transcript 1 (KCNQ1OT1) was implicated in the pathogenesis of various diseases, including cancer, sepsis, diabetic cardiomyopathy, and atherosclerosis. In this study, the influence of KCNQ1OT1 on the proliferation and migration of psoriatic keratinocytes was explained.

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