Open AccessLycopene activity on lung and kidney cancer cells by T2 relaxation time 1H Magnetic Resonance Imaging in vitro
Author(s) -
Katarzyna Pogoda,
Maria Pucka,
Jacek Tabarkiewicz,
Zuzanna Bober,
David Aebisher,
Sabina Galiniak,
Dorota BartusikAebisher
Publication year - 2020
Publication title -
european journal of clinical and experimental medicine
Language(s) - English
Resource type - Journals
eISSN - 2544-2406
pISSN - 2544-1361
DOI - 10.15584/ejcem.2020.1.1
Subject(s) - lycopene , lung cancer , magnetic resonance imaging , cell culture , medicine , in vitro , kidney , a549 cell , cancer , cancer cell , cancer research , nuclear magnetic resonance , pathology , chemistry , biology , radiology , physics , biochemistry , carotenoid , genetics
. The paper presents the results of a study of cell cultures of lung cancer and kidney cancer using lycopene performed using clinical magnetic resonance imaging. Aim. The aim of the study was to evaluate lycopene activity on tumor cell cultures. Material and methods. For this purpose, MR tests were performed using the technique of determining transverse relaxation. Results. Described here studies demonstrated that lycopene may inhibit the growth of A549 and ACHN cell lines. Conclusion. We determine changes in spin lattice relaxavity T2 to monitor treatment of lung cancer cell line A549 and kidney cancer cell line ACHN cells treatment with lycopene.