Open AccessKadar TNF-α dan IL-1β cairan sulkus gingiva setelah pemasangan mahkota akrilik
Author(s) -
Edy Machmud,
Roswita Roswita
Publication year - 2007
Publication title -
journal of dentomaxillofacial science
Language(s) - English
Resource type - Journals
eISSN - 2503-0825
pISSN - 2503-0817
DOI - 10.15562/jdmfs.v6i1.138
Subject(s) - dentistry , wilcoxon signed rank test , bridge (graph theory) , acrylic resin , significant difference , medicine , gingival margin , orthodontics , materials science , surgery , mann–whitney u test , composite material , coating
Cervical margin of fixed denture either jacket crown or bridge, is usually placedsubgingivally for the natural look, however this can sometimes cause gingivalinflammation. Moreover, if the restoration material is acrylic, it sometimes can irritateoral tissue. The aim of this study was to investigate the effect of acrylic, used as fixeddenture material, to gingival tissue reaction. This was an experimental study, using preand post test of 5 acrylic jacket crowns, made to patients in the ProsthodonticDepartment, Dental Hospital of Hasanuddin University. Gingival crevicular fluid (GCF)was collected before preparation, and three weeks after insertion of the jacket crowns,then pro-inflammatory cytokines; TNF-α and IL-1β were examined. The results analyzedby Wilcoxon sign rank test (p<0.05). The results showed the elevation of TNF-α and IL1βconcentration after acrylic jacket crown insertion compare with the concentrationbefore preparation. The conclusion of this study is acrylic restoration material may causegingival inflammation.