Open AccessSignificance of Long Noncoding RNAs in Regenerative Medicine
Author(s) -
Raheleh Amirkhah
Publication year - 2017
Publication title -
journal of genes and cells
Language(s) - English
Resource type - Journals
ISSN - 2410-6887
DOI - 10.15562/gnc.50
Subject(s) - long non coding rna , biology , regenerative medicine , organogenesis , rna , computational biology , paracrine signalling , regeneration (biology) , microbiology and biotechnology , non coding rna , bioinformatics , genetics , stem cell , gene , receptor
Long noncoding RNAs (lncRNAs) are a heterogeneous class of RNAs with generally longer than 200 nucleotides. It has been proposed that LncRNAs as a piece of paracrine action would control cellular pluripotency, differentiation, maintenance and regulate tissue development, organogenesis and regeneration. Next generation sequencing (RNA-seq) has produced huge data about lncRNAs expression profile in different cell types and condition, but understanding the roles and functions of these novel lncRNAs is poorly understood.