Open AccessSingle-organ vasculitis of the cervix accompanying human papillomavirus infection
Author(s) -
Murat Gözüküçük,
Aslı Yarcı Gürsoy,
Duygu Kankaya,
Cem Somer Atabekoğlu
Publication year - 2016
Publication title -
interventional medicine and applied science/interventional medicine and applied science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.195
H-Index - 14
eISSN - 2061-5094
pISSN - 2061-1617
DOI - 10.1556/1646.8.2016.2.111
Subject(s) - medicine , cervix , vasculitis , lesion , human papillomavirus , sex organ , genital tract , cervical canal , pathology , cervical intraepithelial neoplasia , female circumcision , polyarteritis nodosa , gynecology , cervical cancer , cancer , disease , physiology , biology , genetics
Single-organ vasculitis (SOV) has rarely been reported to involve the female genital tract but mostly the uterine cervix. A 39-year-old woman was diagnosed to have a high-grade cervical intraepithelial lesion and was treated by large loop excision of the transformation zone. Histopathological evaluation of the excised specimen confirmed the diagnosis of cervical intraepithelial neoplasia grade III accompanied by human papillomavirus infection. The excised second specimen showed the evidence of vasculitis of medium-sized vessels of the cervix, which is a quite rare form of SOV. It seems to be important to be aware of the localized form of polyarteritis nodosa limited to the female genital tract to prevent unnecessary immunosuppressive therapies.