Open AccessTHE BASIC HYPOTHESIS FOR MECHANOTRANSDUCTION IN SENSORY RECEPTORS
Author(s) -
Ch. Chouchkov,
Iv. Maslarski
Publication year - 2019
Publication title -
trakia journal of sciences
Language(s) - English
Resource type - Journals
eISSN - 1313-3551
pISSN - 1312-1723
DOI - 10.15547/tjs.2019.s.02.006
Subject(s) - mechanotransduction , mechanosensitive channels , mechanoreceptor , sensory system , neuroscience , axolemma , biology , anatomy , sensory receptor , mechanosensation , transduction (biophysics) , receptor , free nerve ending , microbiology and biotechnology , ion channel , biophysics , myelin , central nervous system , biochemistry
One of the most involving problem in the nerve tissue organization is the process of information transduction in the sеnsory receptors and the associated with them sensory cells. The aim of the present report is to review and discuss the data during the latter twenty years about the localization of molecules recently localized in different structural elements of sensory corpuscles and their possible role in the process of mechanotransduction. The most important obligatory parts in the process of mechanotransduction of all sensory receptors are their non-myelinated parts and their bulbous ends or so called nerve endings, like Pacinian and Meissner corpuscles, Krauses bulb, Golgi-Mazzoni corpuscle and Merkel disk. In conclusion, it is still a matter of elucidation in the future to precisely localize the proteins making up the mechanosensitive ion channels. There also exist difficulties regarding the correlation of the physiological with morphological data due to the fact that the receptor axolemma is surrounded by complex cellular structures whose isolation is hard to perform.