Open AccessAssociation of frequency of hereditary hemochromatosis (HFE) gene mutations (H63D and C282Y) with iron overload in beta-thalassemia major patients in Pakistan
Author(s) -
Yasir Sharif,
Saba Irshad,
Anam Tariq,
Sana Rasheed,
Muhammad Hamza Tariq
Publication year - 2019
Publication title -
saudi medical journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 51
eISSN - 1658-3175
pISSN - 0379-5284
DOI - 10.15537/smj.2019.9.24482
Subject(s) - hemochromatosis , hereditary hemochromatosis , medicine , ferritin , mutation , thalassemia , gene mutation , gastroenterology , polymorphism (computer science) , restriction fragment length polymorphism , beta thalassemia , compound heterozygosity , genetics , endocrinology , gene , polymerase chain reaction , genotype , biology
To evaluate any association between the frequency of hereditary hemochromatosis (HFE) gene mutation (H63D and C282Y) and iron overload in beta-thalassemia major (BTM) patients.