Open AccessANTIPROLIFERATIVE PROPERTIES OF ETHANOLIC AND AQUEOUS GRAVIOLA LEAF EXTRACTS ON TONGUE SQUAMOUS CELL CARCINOMA-25.
Author(s) -
Ricardo A. Velázquez-Aponte,
Céline Cassé
Publication year - 2020
Publication title -
journal of medical case reports and reviews
Language(s) - English
Resource type - Journals
eISSN - 2589-8655
pISSN - 2589-8647
DOI - 10.15520/jmcrr.v3i08.201
Subject(s) - annona muricata , cell culture , traditional medicine , apoptosis , in vivo , cell growth , cell , biology , chemistry , medicine , pharmacology , biochemistry , microbiology and biotechnology , genetics
Annona muricata, commonly known as Graviola, soursop or guanabana, is an evergreen tree native to the tropics with a long history of use in ethnomedicine in indigenous communities in Africa and South America. Its active phytoconstituents have provided medicinal benefits against various ailments and diseases such as arthritis, parasitic infection, hypertension, fever, or diabetes. Studies conducted in vitro and in vivo have concluded that Graviola phytocomponents have anti-cancer and anti-tumor properties. One of the characteristics of cancer cells is their uncontrolled proliferation rate. In that sense, molecules that inhibit cell proliferation offer potential therapeutical benefits.