Open AccessEffect of Nonsurgical Periodontal Treatment on Levels of Pyridinoline (ICTP) in the Gingival Crevicular Fluid (GCF)
Author(s) -
MSc Jorge González Quesada,
Sonia Rivera Álvarez
Publication year - 2017
Publication title -
odovtos
Language(s) - English
Resource type - Journals
eISSN - 2215-3411
pISSN - 1659-1046
DOI - 10.15517/ijds.v0i0.27465
Subject(s) - pyridinoline , medicine , periodontitis , dentistry , periodontal disease , chronic periodontitis , gingival and periodontal pocket , bleeding on probing , clinical attachment loss , chemistry , alkaline phosphatase , osteocalcin , biochemistry , enzyme
The destructive periodontal disease affects the tissues supporting the teeth, with the final result in the loss of it; so the research is directed towards identifying objective measures of risk such as biomarkers of destruction. Because studies of biomarkers present in the gingival crevicular fluid (FGC) have reported promising results, it is posible associated markers of tissue degradation with the progression of periodontal disease. The aim of this study is to determine the effect of nonsurgical periodontal treatment on the levels of pyridinoline in the FGC patients with chronic periodontitis. Materials and Methods: FGC samples (before and after treatment), both active and inactive sites determined by the method of tolerance, ICTP levels were measured using the ICTP EIA. Uni Q, the results were analyzed using Stata 7.0 program and the student-test for nonparametric samples Results: ICTP levels decreased significantly after performing non-surgical periodontal treatment (p = 0.0001). Conclusions: According to the results, the ICTP may be a good marker to monitor the effects of nonsurgical periodontal treatment.