Open AccessIdentificação de risco cardiovascular pela razão triglicerídeo/HDL-colesterol em pacientes com doença renal crônica em hemodiálise
Author(s) -
Luciana Leitão Moraes,
Alinne Lorrany Gomes Dos Santos,
Luciana Pereira Pinto Dias,
Dyanara de Almeida Oliveira,
Denise Mafra,
Isabelle Christine Vieira da Silva Martins
Publication year - 2017
Publication title -
scientia medica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.158
H-Index - 7
eISSN - 1980-6108
pISSN - 1806-5562
DOI - 10.15448/1980-6108.2017.3.27369
Subject(s) - medicine , hemodialysis , triglyceride , kidney disease , risk factor , cholesterol , gastroenterology , body mass index , high density lipoprotein , statistical significance , medical record , endocrinology
***Identification of cardiovascular risk by triglyceride/HDL- cholesterol ratio in patients with chronic renal disease in hemodialysis***AIMS: To identify cardiovascular risk by triglyceride/high density lipoprotein cholesterol ratio (TG/HDL-c) and to verify its association with socio-demographic factors, clinical parameters and body mass index in patients with chronic renal disease on hemodialysis.METHODS: Cross-sectional study, in which patients with chronic kidney disease in hemodialysis were evaluated. A non-probability convenience sampling was used. Sociodemographic data were collected through a semi-structured questionnaire interview, and clinical and laboratory data were obtained from the medical records. For the identification of cardiovascular risk, the TG/HDL-c ratio was calculated from plasma triglycerides (mg/dL) and high density lipoprotein cholesterol (mg/dL). The cut-off point for TG/HDL-c considered to be indicative of cardiovascular risk was ≥3.8 mg/dL. For statistical analysis, the chi-square test was used, and the significance level was set at 5% (p <0.05).RESULTS: A total of 71 patients were evaluated, with a mean age of 49.9±13.2 years, being 28 women (50.1±13.2 years) and 43 men (49.7±13.2 years). Among the 71 patients, 31 (43.66%) had cardiovascular risk characterized by the TG/HDL-c ratio ≥3.8 mg/dL. In general, the profile of patients with and without cardiovascular risk was similar. However, in patients with cardiovascular risk there was a higher proportion of males (77.42%), while in those who did not have this risk, the female gender was more frequent (52.50%). This variable showed a significant difference between the groups with and without cardiovascular risk (p=0.011).CONCLUSIONS: In this sample of patients with chronic kidney disease on hemodialysis, the TG/HDL-c ratio identified a high cardiovascular risk index, which was significantly associated with males.