Open AccessLesão anal por papilomavírus humano em mulher vivendo com HIV/aids
Author(s) -
Vanessa Laís Diefenthäler,
Mariele do Amaral Schneider Cardoso,
Janice de Fátima Pavan Zanella,
Paulo Ricardo Moreira,
Janaína Coser
Publication year - 2017
Publication title -
scientia medica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.158
H-Index - 7
eISSN - 1980-6108
pISSN - 1806-5562
DOI - 10.15448/1980-6108.2017.3.27017
Subject(s) - medicine , anal canal , lesion , anal cancer , cervix , squamous intraepithelial lesion , human papillomavirus , sex organ , viral load , physical examination , genital warts , dermatology , dysplasia , hpv infection , gynecology , human immunodeficiency virus (hiv) , pathology , surgery , cervical cancer , syphilis , virology , rectum , cervical intraepithelial neoplasia , cancer , biology , genetics
*** Anal lesion caused by human papillomavirus in a woman living with HIV/AIDS ***AIMS: To describe a case of anal lesion caused by human papillomavirus (HPV) infection in a woman living with HIV/AIDS.CASE DESCRIPTION: A 35-year-old woman, diagnosed with HIV five years ago, reported pruritus ani, anal bleeding, painful defecation, and presence of small warts in the perianal region. The patient was seen at a specialized care center and was subjected to clinical examination with visual inspection, which revealed perianal condyloma. Histopathological examination confirmed the presence of moderate to severe dysplasia associated with HPV-compatible changes. The anal lesion was excised. At the onset of the symptoms, the patient was not on antiretroviral therapy and her HIV viral load was at its highest (2,951 copies/mL) compared with her previous laboratory tests. She had gone through emotional stress and presented with recurrent genital herpes simplex virus infections. These factors may have predisposed her to the development of anal condyloma.CONCLUSIONS: Since HIV infection may alter the history of HPV infection, it is important that screening strategies include cytological analysis of both the cervix and the anal region.