Open AccessПроблеми захворювань молочної залози та перспективи розробки нових протимаститних препаратів
Author(s) -
I.M. Kushnir,
S. D. Murska
Publication year - 2017
Publication title -
naukovij vìsnik lʹvìvsʹkogo nacìonalʹnogo unìversitetu veterinarnoï medicini ta bìotehnologìj ìmenì s.z. g̀žicʹkogo
Language(s) - English
Resource type - Journals
eISSN - 2518-1327
pISSN - 2413-5550
DOI - 10.15421/nvlvet8219
Subject(s) - mastitis , udder , lactation , ice calving , biology , antimicrobial , medicine , veterinary medicine , zoology , pregnancy , microbiology and biotechnology , genetics
Mastitis (Mastitis) is a polyethiological disease, which in most cases (95‒98%) occurs and develops as a result of ingestion of pathogenic microflora in the udder tissue, in particular staphylococci, streptococci, E. coli etc. Diseases of the mammary gland of cows cause significant economic losses to farms of different forms of property, which consist in not getting milk, reducing its quality and crayfish cows, in the first place high-yielding. In addition, the use of milk from cows sick for mastitis threatens the health of people, which is unacceptable.Mastitis occur in both high-yielding and low-productive animals, both, during lactation and in the dry period, regardless of the period of the year. The most widespread, out of all the diseases registered in large dairy commodities, tribal and farms with different forms of ownership is mastitis. Cows most often suffer from mastitis in the first days of the postnatal period, or 10‒15 days after calving, as well as in the period of intense lactation.We emphasize that the creation of new and improved existing anti-mastics preparations, as a rule, are done through the development of multicomponent preparations, which include several active substances from different classes of chemical compounds, which must complement each other in the spectrum of antimicrobial activity.Owing to this, there is a need for advanced research on the creation of more effective anti-mastitis preparations, while those which would not leave residues in tissues and products.Taking into account all abovementioned, the microbiological studies were conducted on 29 samples of milk from cows suffering from clinical and subclinical mastitis in the detection of pathogens. In particular, it was found that for the clinical form of the mastitis, the most commonly isolated monoculture was Staphylococcus aureus (33.7%), Streptococcus agalactiae (29.4%), and in the association of Streptococcus agalactiae and Staphylococcus aureus (22.5%). In the subclinical form of mastitis, the following cultures were identified in the association: Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus agalactiae and Streptococcus dysgalactiae (41.6%); Streptococcus dysgalactiae, Streptococcus agalactiae and Streptococcus uberis (30.4%) Staphylococcus aureus and Staphylococcus epidermidis (24.1%).