Характеристика морфологічних ознак та фізіологічних властивостей штамів сальмонел, ізольованих від птиці і телят

In order to develop effective domestic drugs for the prevention of animal salmonella, in our previous studies, 30 isolates of salmonella were obtained from different collections, including those isolated from epizootic centers of salmonellosis. From this collection, six strains of salmonella were selected as promising production strains for constructing vaccine preparations against salmonellosis and as controls for the study of the immunogenic properties of vaccines.The article presents the results of comparative study of morphological characteristics, tinctorial, culture, biochemical, virulent and antigenic properties of six selected salmonella strains.It was established that the strains studied have morphological characteristics characteristic for salmonella, tinctorial, cultural and biochemical properties and typical for each type of antigenic structure. The highest antigenic activity was S. typhimurium (1:256 ± 154 – 1:192 ± 82) and S. dublin (1:192 ± 51), and the lowest was S. gallinarum (1:72 ± 43). S. infantis and S. gallinarum were not virulent for white mice, while virulent properties of other strains had significant differences.Some regularities in the manifestation of virulent and antigenic properties of the studied salmonella strains were revealed. In particular, it was found that the higher the virulence of the strain, the higher its antigenic activity, and the more distant the term from the date of isolation of the strain from the epizootic center of salmonellosis, the less its virulence, that is, the prolonged storage of strains of salmonella leads to a decrease or to a complete loss of their virulence.