Open AccessБіохімічні показники сироватки крові телят за введення їм імунопрофілактичних засобів проти пневмококової інфекції
Author(s) -
Ya.V. Kissera,
Yu. G. Storchak
Publication year - 2017
Publication title -
naukovij vìsnik lʹvìvsʹkogo nacìonalʹnogo unìversitetu veterinarnoï medicini ta bìotehnologìj ìmenì s.z. g̀žicʹkogo
Language(s) - English
Resource type - Journals
eISSN - 2518-1327
pISSN - 2413-5550
DOI - 10.15421/nvlvet7316
Subject(s) - propolis , organism , immune system , vitamin e , immunostimulant , blood serum , medicine , immunology , biology , antioxidant , microbiology and biotechnology , pharmacology , traditional medicine , biochemistry , paleontology
Given that the main role in ensuring sufficient immunobiological reactivity and resistance of the animal organism is given to optimal provision of the need for these animals in vitamins, macro- and microelements, and inadequate vitamin, mineral, including micromineral nutrition causes in animals the disturbance of the immune system function, reduces the resistance of the organism to infections, increases the number of chronic diseases, the question arose about the development of a new preventive and immunostimulating means. A special place in the pathologies and low resistance of the animal organism to bacterial diseases is the deficit of Ferum, Selenium and a number of vitamins in the diet of animals. The results of the determination of biochemical parameters of blood serum of young cattle after injection of specific means for preventing pneumococcal infection are given in the article: the inactivated vaccine against streptococcal and staphylococcal infections of animals, the developed prophylactic drug Pnevmo-Pro, and Pnevmo-Pro in combination with immunostimulant Selefer. The obtained results of studies showed an increase in the basic biochemical parameters of blood serum of experimental animals after the injection of prophylactic agents: the content of total protein, albumins, an increase in the concentrations of Calcium, Phosphorus and Ferum. The developed preventive agent «Pnevmo-Pro» in its composition contains two components: Streptococcus pneumoniae and alcohol-water extract of propolis, which has antiinflammatory and immunomodulatory properties. Experimental studies have shown that propolis, due to its antiinflammatory and antioxidant properties, prevents the development of pneumonia. Despite the presence of antibacterial properties, prolonged use of propolis does not lead to dysbiosis. The expediency of using immunoprophylactic drugs in combination with organic immunostimulants is proved in order to increase the resistance of animals in biogeochemical zones, endemic for a number of microelements.