ПОШИРЕННЯ, ЕТІОЛОГІЯ ТА ДІАГНОСТИКА ГІПОТИРЕОЗУ У КОРІВ ЖИТОМИРСЬКОГО ПОЛІССЯ

Zhytomyr Polissya of Ukraine is part of the biogeochemical zones, which is characterized by insufficient content of biotic trace elements, including iodine, lack of which in the environment is a common biological and medical problem. Animals, which being in a single food chain with a man, have geochemical and environmental impacts in a greater degree. The main reason for the decrease in the functional activity of the thyroid gland in cows is low iodine content in soils and, as a consequence, in animal feed and their contamination with radionuclides – 137Cs and 90Sr. Low total contents in the soil of the territory of the synergists of iodine – cobalt – 1.7 – 2.5 mg/kg (optimal 7 – 30), copper –1.1 – 2.7 (15 – 60), zinc – 13.2 – 31.0 mg/kg (30 – 70), and in some places, and manganese contribute to the development of this disease.The symptoms of iodine deficiency, which is typical for hypothyroidism: dryness and hyperkeratosis of the skin, the long hair site the withers, anemone conjunctiva, enophthalm, bradycardia, myxedema, thyroid enlargement were installed by clinical studies. So, 90% of the cows revealed hypofunction of the thyroid gland : content thyroxine the blood serum was in the range 28.3 to 54.7 nmol/l and averaged a 43.8 ± 2.7 nmol/l (3.4 ± 0.21 mg/100 ml).Micronutrient deficiency causes a disruption of haematopoiesis and the development of anemia in 85% of cows that expressed agociting (75 – 80%) and olgahoney (of 41.7 – 66.7 percent). Anemia, mainly macrocytic and hyperchromic, rarely normochromic.Erythrogramma of cows notes longer left part, compared with animals a safe zone, that indicates on a significant number of «old» age of red blood cells, and stretched the right part that is due to the increased number of more resistant to hemolysis immature «young»erythrocytes.