Open AccessПАТОМОРФОЛОГІЯ ПІДШЛУНКОВОЇ ЗАЛОЗИ СОБАК ЗА ХРОНІЧНОГО ПАНКРЕАТИТУ
Author(s) -
L. P. Horalskyi,
I. M. Sokulskyi,
Н. В. Демус
Publication year - 2016
Publication title -
naukovij vìsnik lʹvìvsʹkogo nacìonalʹnogo unìversitetu veterinarnoï medicini ta bìotehnologìj ìmenì s.z. g̀žicʹkogo
Language(s) - English
Resource type - Journals
eISSN - 2518-1327
pISSN - 2413-5550
DOI - 10.15421/nvlvet7010
Subject(s) - pancreas , pancreatitis , pathology , cytoplasm , connective tissue , endocrine system , enteroendocrine cell , pancreatic islets , medicine , islet , biology , anatomy , endocrinology , diabetes mellitus , biochemistry , hormone
On the basis of morphological, pathologoanatomic, histological and morphometric researches, the morphological structure of clinically healthy dog's pancreas and at chronic pancreatitis were determined in the article. Having used morphometric researches were found that the absolute mass of dog's pancreas at chronic pancreatitis towards clinically healthy dogs, increased for 1,28 times from 29.3 ± 3.0 g in healthy animals to 38.33 ± 7.02 g in ill ones. The relative weight of organ increased in 1.19 times and was 0.19 ± 0.04 % in comparison with the control 0.16 ± 0.03%.Owing to the histological researches, was found the structure breach of pancreatocites. In acinar cells, cytoplasm zoning did not occur, pancreatocites poorly perceived coloration and contained inclusions in the form of drops. The kariolisis cores was present. In Pancreatic islets focal hemorrhage were observed as well as the destruction of endocrine cells. Inter particle connective tissue layer were thickened and in organ's glandular tissue were presented bands that penetrate and branch in depth of a particle. It was determined on the basis of morphometric researches that the value of pancreacites and their nuclei in ill animals truly (р < 0,05) increases and was namely 455.51 ± 33.24 та 54.90 ± 7.24 mcm3 (in clinically healthy ones namely – 356.06 ± 11.37 та 33.69 ± 1.62 mcm3). The nucleus cytoplasm relation of pancreacites of pancreas in dogs at chronic pancreatitis towards the relation to clinically healthy dogs, increased for 1.44 times and was 0.177 ± 0.04. In dogs of the control group such indicator was 0.123 ± 0.001.