Open AccessРЕДОКС-ПОТЕНЦІАЛ ТА СТАН ПЕРЕКИСНОГО ОКИСНЕННЯ ЛІПІДІВ КРОВІ КОРІВ, ЩО УТРИМУЮТЬСЯ У ЕКОЛОГІЧНО НЕСПРИЯТЛИВИХ УМОВАХ
Author(s) -
І. В. Чала,
V. Rusak
Publication year - 2016
Publication title -
naukovij vìsnik lʹvìvsʹkogo nacìonalʹnogo unìversitetu veterinarnoï medicini ta bìotehnologìj ìmenì s.z. g̀žicʹkogo
Language(s) - English
Resource type - Journals
eISSN - 2518-1327
pISSN - 2413-5550
DOI - 10.15421/nvlvet6640
Subject(s) - chemistry , peroxide , environmental chemistry , nuclide , radionuclide , antioxidant , lipid peroxidation , contamination , radiolysis , redox , lipid peroxide , radioactive contamination , glutathione , food science , radiochemistry , biochemistry , radical , ecology , biology , inorganic chemistry , organic chemistry , physics , enzyme , quantum mechanics
The paper highlights the investigations into the effects of the complex of unfavorable ecological factors which appear as a result of Chernobyl-derived contamination of farm lands on the intensity of peroxide oxidation of lipids and glutathione chain of the antioxidant system of dairy cows, as well as on the changes in the redox-potential of blood. The territory that suffered from Chernobyl-derived radionuclide contamination is characterized by the unfavorable ecological situation which is connected with the increase in the radioactive load on animals, as well as with the decrease in the part of soluble (exchange) form of biogenic mineral elements of soils. The above conditions make it possible to initiate a complex of biochemical changes caused by water radiolysis, by the increase in the active forms of oxygen and by the protection of the body from the products of peroxidation which appear as a result of the effects of radiolysis products. The investigation is aimed at determining the redox-potential of venous blood and separate indices of the peroxide oxidation of lipids and the antioxidant system of blood in cows kept in the zone which was contaminated by the man-caused radio nuclides , as compared with cows kept in the zone with background values of radioactivity and ᶨ- irradiation emissive power. The investigation results make it possible to establish that in the blood of cows kept under ecologically unfavorable conditions one can observe the increase in the concentration of the products of lipid peroxide oxidation: hydroperoxide lipids and malone dialdehyde. Under the above conditions one can establish the changes in the activity of the glutathione chain of the antioxidant system: the decrease in the part of renewed glutathione and the authentic increase in the part of oxidized glutathione and the decrease in the activity of glutathione reductase as compared with cows kept under ecologically favorable conditions. It has been established that under the effects of unfavorable ecological factors one can observe the increase in the positive redox-potential of blood which testifies to the disturbances between oxidized and renewed potentials.