Open AccessТОКСИКОЛОГІЧНА ОЦІНКА ПРЕПАРАТУ «БІОКОНТАКТ ПЛЮС» ДЛЯ МЕДОНОСНОЇ БДЖОЛИ
Author(s) -
S. F. Tushak,
T.O. Romanishina
Publication year - 2016
Publication title -
naukovij vìsnik lʹvìvsʹkogo nacìonalʹnogo unìversitetu veterinarnoï medicini ta bìotehnologìj ìmenì s.z. g̀žicʹkogo
Language(s) - English
Resource type - Journals
eISSN - 2518-1327
pISSN - 2413-5550
DOI - 10.15421/nvlvet6637
Subject(s) - toxicity , disinfectant , acute toxicity , toxicology , drug , fish <actinopterygii> , medicine , pharmacology , biology , pathology , fishery
The article is devoted to the toxicological estimation of the disinfectant of new generation «Biocontact plus» for bees using the method of contact and oral toxicity definition. The experiments were carried out at the laboratory of Zhytomyr National Agroecological University at the faculty of Veterinary Medicine, Department of Microbiology, Pharmacology and Epizootology. Definition of contact and oral toxicity was carried out by the method of bees’ group treatment in entomophilic gardens and isolators. The duration of the observation period: for acute phase – 48 hour, for chronic phase – 20 days. It was concluded, that the contact use of the drug results in temporary effect, if concentration is 0.3%. While estimating the toxicity in the stomach, the effect of acute toxicity was observed at the level of concentration 0.3%. If the drug is used with the concentration 0.1% and 0.15%, is has stimulating and activating effect. If the level of concentration is low (0.03%, 0.01%), no positive changes in the vital functions of the bees were observed. The possibility of use the drug in the function of stimulator for bees using the method of nutrition additives with the level of concentration 0.1% and 0.15% was proved.It is necessary to study the possibility of the usage of the drug in the function of stimulator for bees using the method of nutrition additives with the level of concentration 0.1% and 0.15% taking into consideration the changes of physiological markers (cytological and morphological hemolymph composition, development of lipid droplet), assessment of influence on the economically useful markers of families, changes in sanitary and hygiene behaviour of bees.