Open AccessГІСТОЛОГІЧНІ ЗМІНИ В ТЕЛЯТ ЗА ГОСТРОГО ПЕРЕБІГУ САЛЬМОНЕЛЬОЗУ
Author(s) -
V. Lisova,
А. Ф. Павленко,
N. Romanenko
Publication year - 2016
Publication title -
naukovij vìsnik lʹvìvsʹkogo nacìonalʹnogo unìversitetu veterinarnoï medicini ta bìotehnologìj ìmenì s.z. g̀žicʹkogo
Language(s) - English
Resource type - Journals
eISSN - 2518-1327
pISSN - 2413-5550
DOI - 10.15421/nvlvet6625
Subject(s) - pathology , lymph , spleen , serous fluid , lymphatic system , pathogenesis , hyperplasia , parenchyma , biology , mesenteric lymph nodes , enteritis , medicine , immunology
The results of study of histological changes in calves by age of 20 – 40 days at acute salmonellosis infection are presented. At a histological research the most expressed changes were registered in the liver, thin intestine and lymphoid organs that contingently reproduction here of the causative agent. At acute form of salmonellosis in calves of this age-grade characteristic histological changes include: submilliar, intralobular, coagulativ, areactive foci of necrosis in a liver; cell granuloma in a liver; the acute diffusive serous-catarrhal enteritis with a hemorrhagic accent; serous lymphadenitis of intestinal lymph nodes; the acute diffusive catarrhal abomasitis. Also nonspecific, but constant morphological signs of salmonellosis are hyperplasia Peyer’s patches of a small intestine, intestinal lymph nodes, spleen and dystrophic changes of parenchymal organs.An analysis and theoretical ground of pathogenetic mechanisms of the educed microstructural changes are conducted. It is shown that in pathogenesis of salmonellosis an important role is played bacteriaemia and toxinaemia, which result to the defeat of endothelia of vessels and blood cells with subsequent violation of mechanisms of haemostasis гand development of the infectiously-toxic shock.