Open AccessАНТИМІКРОБНА АКТИВНІСТЬ ЕТАНОЛЬНОГО ЕКСТРАКТУ SERRATULA CORONATA L. (ASTERACEAE) ЗА ІНТРОДУКЦІЇ В ЖИТОМИРСЬКОМУ ПОЛІССІ
Author(s) -
I. Ivashchenko
Publication year - 2016
Publication title -
bìologìčnij vìsnik melìtopolʹsʹkogo deržavnogo pedagogìčnogo universitetu ìmenì bogdana hmelʹnicʹkogo
Language(s) - English
Resource type - Journals
eISSN - 2226-9010
pISSN - 2225-5486
DOI - 10.15421/201616
Subject(s) - staphylococcus aureus , escherichia coli , microbiology and biotechnology , candida albicans , pseudomonas aeruginosa , antimicrobial , biology , minimum bactericidal concentration , bacteria , minimum inhibitory concentration , chemistry , biochemistry , genetics , gene
Antimicrobial properties of Serratula coronata L ., introduced in Zhytomyr Polissya, were studied against test cultures of Escherichia coli (coliform bacillus) UCM B-906 (ATCC 25922), Staphylococcus aureus (golden staphylococcus) UCM B-904 (ATCC 25923), Pseudomonas aeruginosa (blue pus bacillus) UCM B-900 (ATCC9027), Candida albicans UCM Y-(ATCC 885-653). Serratula coronata L. 40 % ethanol extract showed potent antimicrobial effect against gram-positive bacteria Staphylococcus aureus . Compared with the solvent, MIC (minimal inhibitory concentration) and MBC (minimal bactericidal concentration) increased 32 and 8 times, respectively. The other microorganisms’ cultures demonstrated much lower sensitivity. The study revealed less significant effect of the extract against Candida albicans, Pseudomonas aeruginosa, and it failed to display any bactericidal/fungicidal effect against gram-negative strains of Escherichia coli, Pseudomonas aeruginosa and fungus Candida albicans. The data obtained experimentally show that further study of Serratula coronata L . and its application as the basis for new pharmaceutical anti-staphylococcus preparations may be considered promising and having a great potential.