АНТИМІКРОБНА АКТИВНІСТЬ ЕТАНОЛЬНОГО ЕКСТРАКТУ SERRATULA CORONATA L. (ASTERACEAE) ЗА ІНТРОДУКЦІЇ В ЖИТОМИРСЬКОМУ ПОЛІССІ

 Antimicrobial properties of  Serratula coronata  L .,  introduced in Zhytomyr Polissya, were studied against test cultures of  Escherichia coli  (coliform bacillus) UCM B-906 (ATCC 25922),  Staphylococcus aureus (golden staphylococcus) UCM B-904 (ATCC 25923),  Pseudomonas aeruginosa  (blue pus bacillus) UCM B-900 (ATCC9027),  Candida albicans  UCM Y-(ATCC 885-653). Serratula coronata  L.   40 % ethanol extract showed potent antimicrobial effect against gram-positive bacteria  Staphylococcus aureus . Compared with the solvent, MIC (minimal inhibitory concentration) and MBC (minimal bactericidal concentration) increased 32 and 8 times, respectively. The other microorganisms’ cultures demonstrated much lower sensitivity. The study revealed less significant effect of the extract against  Candida albicans, Pseudomonas aeruginosa,  and it failed to display any bactericidal/fungicidal effect against gram-negative strains of  Escherichia coli, Pseudomonas aeruginosa  and fungus  Candida albicans. The data obtained experimentally show that further study of  Serratula coronata  L .  and its application as the basis for new pharmaceutical anti-staphylococcus preparations may be considered promising and having a great potential.