Dual Anti-platelet Therapy after Coronary Stenting: Rationale for Personalized Duration of Therapy

There is controversy regarding the appropriate duration of dual anti-platelet therapy after coronary stenting. Recent guidance has been updated to reflect improved outcomes after second-generation drug-eluting stenting, but a standard duration for all patients is not rational given the different risks for ischemic and bleeding complications. This paper reviews the data for short- and long-term dual anti-platelet therapy and considers approaches for developing a personalized strategy.