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Percutaneous Treatment of Non-paroxysmal Atrial Fibrillation: A Paradigm Shift from Pulmonary Vein to Non-pulmonary Vein Trigger Ablation?
Author(s) -
Domenico G. Della Rocca,
Sanghamitra Mohanty,
Chintan Trivedi,
Luigi Di Biase,
Andrea Natale
Publication year - 2018
Publication title -
arrhythmia and electrophysiology review
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.008
H-Index - 18
eISSN - 2050-3377
pISSN - 2050-3369
DOI - 10.15420/aer.2018.56.2
Subject(s) - pulmonary vein , medicine , cardiology , ablation , catheter ablation , atrial fibrillation , paroxysmal atrial fibrillation , percutaneous , antrum , vein , catheter , surgery , stomach
Pulmonary vein antrum isolation is the most effective rhythm control strategy in patients with paroxysmal AF. However, catheter ablation of non-paroxysmal AF has a lower success rate, even when persistent isolation of pulmonary veins (PVs) is achieved. As a result of arrhythmia-related electophysiological and structural changes in the atria, sites other than the PVs can harbour triggers. These non-PV triggers contribute to AF relapse. In this article, we summarise the rationale and current evidence supporting the arrhythmogenic role of non-PV triggers and our ablation approach to patients with non-paroxysmal AF.

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