Open AccessBloodstream Infections in Children With Sickle Cell Disease: 2010–2019
Author(s) -
Marianne E. Yee,
Kristina Lai,
Nitya Bakshi,
Joanna K. Grossman,
Preeti Jaggi,
Alexander Mallis,
Yun F. Wang,
Robert C. Jerris,
Peter A. Lane,
İnci Yıldırım
Publication year - 2021
Publication title -
pediatrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.611
H-Index - 345
eISSN - 1098-4275
pISSN - 0031-4005
DOI - 10.1542/peds.2021-051892
Subject(s) - medicine , odds ratio , incidence (geometry) , streptococcus pneumoniae , bacteremia , haemophilus influenzae , anemia , blood culture , pediatrics , sickle cell anemia , antibiotics , disease , microbiology and biotechnology , physics , optics , biology
Children with sickle cell disease (SCD) are at increased risk for bloodstream infections (BSIs), mainly because of functional asplenia. Immunizations and antibiotic prophylaxis have reduced the prevalence of invasive bacterial infections, but contemporary analysis of BSI in children with SCD is limited.