Open AccessA Rare Pulmonary Manisfestation of Kahler's disease
Author(s) -
Gaurav Baheti,
Ankur Jain
Publication year - 2018
Publication title -
journal of medical research and innovation
Language(s) - English
Resource type - Journals
ISSN - 2456-8139
DOI - 10.15419/jmri.115
Subject(s) - multiple myeloma , differential diagnosis , malignancy , pathology , parenchyma , immunoglobulin light chain , bone marrow , medicine , interstitial lung disease , infiltration (hvac) , rare disease , antibody , lung , chemistry , disease , immunology , materials science , composite material
Kahler's disease also known as Multiple Myeloma (MM) is one of the most dangerous primary malignancy of the bone marrow which is significant for its plasma cells proliferation and abnormal growth of monoclonal immunoglobulins (including M protein and light chain proteins: κ and λ). Excess amount of M protein is a potential blood thickener due to its effects on viscosity, while an excess amount of light chains could lead to an end-organ damage.
MM presenting as Interstital Lung Disease (ILD) has been documented in very rare occasions till date and hence, we are presenting forward a letter showing the importance of considering MM as a differential when a patient presents with ILD features by presenting one such case of a patient who was diagnosed with MM and developed ILD secondary due to infiltration of Myeloma cells in the parenchyma of the lungs.