Open AccessEffect of Vitamin D deficiency in lower extremity and pulmonary venous thromboembolism
Author(s) -
Khatereh Dehghani,
Aygin Nowrouzi,
Amir Hossein Pourdavood,
Zhila Rahmanian
Publication year - 2019
Publication title -
biomedical research and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.135
H-Index - 1
ISSN - 2198-4093
DOI - 10.15419/bmrat.v6i4.535
Subject(s) - medicine , vitamin d deficiency , vitamin d and neurology , vitamin , gastroenterology , venous blood , endocrinology
Vitamin D deficiency increases inflammation and dysfunction of pancreas betacells, resulting in atherosclerotic disorders, cerebrovascular disorder, and CVDs.
Methods: In the present cross-sectional study, vitamin D was evaluated in the plasma of 42 patients with lower extremity DVT or PE, as well as 42 healthy controls. Using the chemiluminescence assay, the plasma vitamin D levels were determined. After collection, the blood samples were examined within 60 minutes. Vitamin D levels were classified as sufficient, insufficient, and deficient (> 30 ng/mL, 20- 29 ng/mL, and < 20 ng/mL, respectively).
Results: The prevalence of deficiency in vitamin D was higher in the cases than the controls. The two groups were significantly different regarding vitamin D levels (p = 0.024). Based on the vitamin D classification, deficiency was reported in 30 (71.4%) patients and 18 (42.9%) controls.
Conclusion: Our findings indicated that VTE patients had lower concentration of vitamin D, and the correlation between VTE and vitamin D deficiency was confirmed.