Open AccessID: 1033 Case report: Results of the first case of Stem cell transplantation from cord blood cryopreservation for β-thalassemia patient at Vinmec International Hospital
Author(s) -
Phu Nt,
Phuong T M Dam,
Dung Nt,
Lan Pt,
Liem Nt
Publication year - 2017
Publication title -
biomedical research and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.135
H-Index - 1
ISSN - 2198-4093
DOI - 10.15419/bmrat.v4is.309
Subject(s) - medicine , cord blood , thalassemia , umbilical cord , transplantation , sibling , hematopoietic stem cell transplantation , stem cell , umbilical cord blood transplantation , pediatrics , surgery , immunology , biology , psychology , developmental psychology , genetics
Background: To report the result of first case of β thalassemia, which is successfully transplanted by using allogeneic cord blood at the Vinmec International Hospital.
Methods: Male patient, born in January 2014, was diagnosed with β thalassemia at 3 months of age. Patient was received cord blood transplantation from his younger sibling who matches HLA index of 10/10 in August 2016.
Results: The number of cells in cord blood met high quality and after 30 days of transplantation, engraftment of patient fully developed with the Chimerism test was 100%. After 3 months of follow-up, it was demonstrated that the transplantation was successful.
Conclusion: We present an effective case of hematopoietic stem cell transplantation from human umbilical cord blood of sibling for treatment of thalassemia.