Open AccessAssociation between cigarette smoking behavior and infertility in women: a case-control study
Author(s) -
Mandana Sarokhani,
Yousef Veisani,
Akbar Mohamadi,
Ali Delpisheh,
Kourosh Sayehmiri,
Ashraf Direkvand-Moghadam,
Mahshid Aryanpur
Publication year - 2017
Publication title -
biomedical research and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.135
H-Index - 1
ISSN - 2198-4093
DOI - 10.15419/bmrat.v4i10.376
Subject(s) - infertility , medicine , nicotine , odds ratio , fertility , logistic regression , demography , smoking cessation , tobacco control , obstetrics , environmental health , population , public health , pregnancy , genetics , nursing , pathology , sociology , biology
Introduction: The effects of smoking on decreasing the chance of fertility in women have been acknowledged but some aspects, such as smoking behavior, are currently unclear. The present study aims to evaluate the relationship between smoking traits and infertility in women through a comparative study with fertile women.
Methods: This case-control study was conducted on 350 women (177 infertile and 173 fertile) in March-May 2014. Sampling was performed in two phases. Demographic and reproductive data were collected by questionnaires- for demographics and the Fagerstrom Test for Nicotine Dependence (FTND)). The total score of questionnaires was ten. The participants were divided into 3 groups: “Low Nicotine” dependency (0-4), “Moderate Nicotine” dependency (5) and “High Nicotine” dependency (6-10). To examine the relationship between smoking and infertility, both the chi-square test and logistic regression tests were used.
Results: Tobacco use in infertile women was greater than that for fertile women (23.7% vs. 16.1%, respectively, P = 0.012); in fact, 16.7% of tobacco consumers had high nicotine dependency. Medium and low nicotine dependency were seen in 5.6% and 77.8% of tobacco consumers, respectively. Positive history of smoking increased the odds of being infertile (OR 2.88; 95% CI: 1.56- 4.92) and risk for infertility was associated with low nicotine dependency (OR 3.12; 95% CI 1.16-8.09).
Conclusion: Low and high nicotine dependency increased the risk of infertility. Considering the physical, mental, social and economic effects of infertility in society, the negative effects of smoking on fertility should be considered and/or included in the training package for health service providers.
Peer Review Details
Peer review method: Single-Blind (Peer-reviewers: 02) Peer-review policy
Plagiarism software screening?: Yes
Date of Original Submission: 29 August 2017
Date accepted: 02 October 2017
Peer reviewers approved by: Dr. Lili Hami
Editor who approved publication: Dr. Phuc Van Pham