Open AccessStructure Verification of Small Molecules
Author(s) -
Herbert Thiele,
George McLeod,
Ilmari Krebs
Publication year - 2022
Publication title -
ukrainian journal of physics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.213
H-Index - 17
eISSN - 2071-0194
pISSN - 2071-0186
DOI - 10.15407/ujpe56.8.769
Subject(s) - mass spectrometry , isotope , molecule , mass spectrum , analytical chemistry (journal) , materials science , computational physics , chemistry , physics , chromatography , nuclear physics , organic chemistry
The high mass accuracy of the MS and MS/MS data provided by the new generation of ESI-TOF- and ESI-Q-TOF mass spectrometers provides an accurate determination of molecular weight, which is used specifically for the structural verification and purity determination of substances. The high separation of the isotope profile for both MS and MS/MS spectra affords further dimensions of information to achieve precise molecular formula determination.