Open AccessQuality of Life after 10 Years of Liver Transplantation
Author(s) -
Micheli Fortunato Domingos,
Júlio Cézar Uili Coelho,
Isabel Roldo Nogueira,
Mônica Beatriz Parolin,
Jorge Eduardo Fouto Matias,
Alexandre Coutinho Teixeira de Freitas,
Clementino Zeni Neto,
Eduardo J.B. Ramos
Publication year - 2020
Publication title -
journal of gastrointestinal and liver diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.641
H-Index - 48
eISSN - 1842-1121
pISSN - 1841-8724
DOI - 10.15403/jgld-2829
Subject(s) - medicine , quality of life (healthcare) , vitality , cirrhosis , population , liver transplantation , medical record , sf 36 , mental health , transplantation , surgery , health related quality of life , psychiatry , environmental health , disease , philosophy , nursing , theology
Aim: This study goal was to evaluate the long-term quality of life of patients who underwent cadaveric liver transplants (CLT) in two Brazilian hospitals.
Methods: Medical records of all patients who underwent CLT and survived over 10 years were revised. The international validated questionnaire Short-Form 36 was employed to assess the quality of life. Patients data were obtained from electronic medical records and study protocols.
Results: A total of 342 patients underwent CLT, of which 129 were alive and 93 fully answered the questionnaire and were included in the study. The group consisted of 62 men (66.6%) and 31 women (33.4%), with average age of 40.1±15.9 years. Follow-up time was 16±4.1 years. The most common indication of CLT was hepatic cirrhosis caused by hepatitis C virus, 24.7%. Transplanted patients had lower scores than the general population in mental health [62.9 (95%CI: 60.1-65.7,) vs. 74.5, p < 0.001]. In all other domains, transplanted patients had similar (emotional aspect limitiation, pain, and general health status) or superior (physical aspect limitation, social aspects, functional capacity, and vitality) scores than the general population. Functional capacity score was lower in patients with long-term complications, who were aged more than 50-years, and unemployed.
Conclusions: The quality of life in patients with more than 10 years after CLT was similar or superior than the general population, except for the mental health domain.