Open AccessImplementation and Evaluation of Preimplantation Genetic Testing at Vilnius University Hospital Santaros Klinikos
Author(s) -
Eglė Stukaitė-Ruibienė,
Živilė Gudlevičienė,
Andrė Amšiejienė,
Evelina Dagytė,
Rimantas Gricius,
Kristina Grigalionienė,
Algirdas Utkus,
Diana Ramašauskaitė
Publication year - 2022
Publication title -
acta medica lituanica
Language(s) - English
Resource type - Journals
eISSN - 2029-4174
pISSN - 1392-0138
DOI - 10.15388/amed.2022.29.2.9
Subject(s) - genetic testing , infertility , in vitro fertilisation , retrospective cohort study , medicine , gynecology , population , obstetrics , biology , pregnancy , genetics , environmental health
The most effective treatment of infertility is in vitro fertilization (IVF). IVF with Preimplantation Genetic Testing (PGT) allows to identify embryos with a genetic abnormality associated with a specific medical disorder and to select the most optimal embryos for the transfer. PGT is divided into structural rearrangement testing (PGT-SR), monogenetic disorder testing (PGT-M), and aneuploidy testing (PGT-A). This study mostly analyzes PGT-SR, also describes a few cases of PGT-M. The aim of this study was to implement PGT procedure at Vilnius University Hospital Santaros Klinikos (VUHSK) Santaros Fertility Centre (SFC) and to perform retrospective analysis of PGT procedures after the implementation.