Open AccessAtypical Fibroxanthoma: An unexpected cause of hemoptysis
Author(s) -
Konstantinos Mantzouranis,
Vasiliki Georgakopoulou,
Serafeim Chlapoutakis,
Despoina Melemeni,
Christos Damaskos,
Nikolaos Garmpis,
Pagona Sklapani,
Νικόλαος Τράκας,
Xanthi Tsiafaki
Publication year - 2021
Publication title -
acta medica lituanica
Language(s) - English
Resource type - Journals
eISSN - 2029-4174
pISSN - 1392-0138
DOI - 10.15388/amed.2021.28.1.16
Subject(s) - atypical fibroxanthoma , medicine , head and neck , sarcoma , dermatology , pathology , undifferentiated pleomorphic sarcoma , lesion , surgery , immunohistochemistry , soft tissue sarcoma
Atypical fibroxanthoma is an infrequent, low-grade superficial cutaneous neoplasm, usually presenting as a nodule or plaque of red color. It is considered as a superficial variant of pleomorphic dermal sarcoma. Although atypical fibroxanthoma has similar histologic features to pleomorphic dermal sarcoma, it has less aggressive behavior. Atypical fibroxanthoma usually occurs on sun-exposed regions of the head and neck of elderly patients. Ultraviolet light, specific genetic mutations and administration of immunosuppressive agents to transplant recipients have been associated with the pathogenesis of the tumor. The prognosis is typically excellent when treated with complete excision of the primary lesion. This report describes the rare case of a 84-year-old man with hemoptysis due to metastatic cutaneous atypical fibroxanthoma.