Open AccessThe Function of MicroRNAs in Autoimmune Diseases
Author(s) -
Patricia Mendes Demo
Publication year - 2022
Publication title -
science insights
Language(s) - English
Resource type - Journals
eISSN - 2372-8191
pISSN - 2329-5856
DOI - 10.15354/si.22.re033
Subject(s) - microrna , biology , autoimmune disease , gene , function (biology) , immunology , gene expression , computational biology , bioinformatics , genetics , antibody
MicroRNAs (miRNAs) are a family of non-coding single-stranded RNAs with a length of around 18-25 nucleotides that play a critical role in the control of gene expression, cell proliferation, differentiation, and apoptosis, as well as biological growth and development and illness. Autoimmune diseases are a group of disorders characterized by tissue and organ damage and resulting dysfunction as a result of autoimmune responses. Numerous studies have discovered that aberrant expression of certain miRNAs may serve as biomarkers for early detection of these diseases or as therapeutic targets. The biological properties of miRNAs and their significance in autoimmune illnesses are discussed in this review.