Open AccessCan a Digital Therapy Using Sound and Light Reset the Balance of Alzheimer’s Disease?
Author(s) -
Julia N. Wood,
Carson Will
Publication year - 2022
Publication title -
science insights
Language(s) - English
Resource type - Journals
eISSN - 2372-8191
pISSN - 2329-5856
DOI - 10.15354/si.22.pe005
Subject(s) - neuroscience , dementia , balance (ability) , disease , optogenetics , medicine , psychology , cognition , reset (finance) , cognitive decline , audiology , pathology , financial economics , economics
Alzheimer’s disease (AD) is a degenerative cognition-declining disease with no clear understanding of the underlying mechanisms. Currently, no effective therapeutics are available for AD. Amyloid-β (A-β) plaques and tau tangles were considered as the contributing factors to the development of AD. In contrast, controversial exists due to efforts focusing on A-β as a pharmacological therapeutic target was failed. Emerging evidence appeared for the external stimuli applied through vision (LED) and hearing (~40Hz) to certain intensity to dementia subjects with promising results such as reducing A-β and tau tangles in the brain tissue, increasing the brain volume reducing the decline of daily activities and mental status. This optogenetic and sound-derived digital therapeutic maneuver provides a striking way for conquering the development of AD.