gQTL: A Web Application for QTL Analysis Using the Collaborative Cross Mouse Genetic Reference Population
Author(s) -
Kranti Konganti,
Andre Ehrlich,
Ivan Rusyn,
David W. Threadgill
Publication year - 2018
Publication title -
g3 genes genomes genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.468
H-Index - 66
ISSN - 2160-1836
DOI - 10.1534/g3.118.200230
Subject(s) - quantitative trait locus , population , computer science , graphical user interface , software , inbred strain , user interface , biology , genetics , programming language , gene , demography , sociology
Multi-parental recombinant inbred populations, such as the Collaborative Cross (CC) mouse genetic reference population, are increasingly being used for analysis of quantitative trait loci (QTL). However specialized analytic software for these complex populations is typically built in R that works only on command-line, which limits the utility of these powerful resources for many users. To overcome analytic limitations, we developed gQTL, a web accessible, simple graphical user interface application based on the DOQTL platform in R to perform QTL mapping using data from CC mice.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom