Open AccessInflammatory biomarkers in the evaluation of pediatric endogenous Cushing syndrome
Author(s) -
Rachel Wurth,
Megan Rescigno,
Chelsi Flippo,
Constantine A. Stratakis,
Christina Tatsi
Publication year - 2022
Publication title -
european journal of endocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.897
H-Index - 148
eISSN - 1479-683X
pISSN - 0804-4643
DOI - 10.1530/eje-21-1199
Subject(s) - medicine , lymphocyte , receiver operating characteristic , neutrophil to lymphocyte ratio , absolute neutrophil count , area under the curve , endocrinology , morning , gastroenterology , immunosuppression , neutropenia , toxicity
Inflammatory biomarkers, such as absolute neutrophil and lymphocyte counts, neutrophil-to-lymphocyte ratio (NLR), platelet (PLT)-to-lymphocyte ratio (PLR) and monocyte-to-lymphocyte ratio (MLR), are associated with the progression and development of several disorders. Although patients with Cushing syndrome (CS) have immunosuppression with altered leucocyte counts, the profile of the inflammatory biomarkers in these patients has not been extensively studied.