Open AccessPreconditioning of Human Skeletal Myoblast with Stromal Cell-derived Factor-1Ձ Promotes Cytoprotective Effects against Oxidative and Anoxic Stress
Author(s) -
Ibrahim Elmadbouh,
Husnain Kh Haider,
Muhammad Ashraf,
Juan Carlos Chachques
Publication year - 2011
Publication title -
international journal of stem cells
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.569
H-Index - 23
eISSN - 2005-5447
pISSN - 2005-3606
DOI - 10.15283/ijsc.2011.4.1.50
Subject(s) - transfection , stromal cell , flow cytometry , immunostaining , microbiology and biotechnology , blot , andrology , cell culture , cell , medicine , biology , immunology , immunohistochemistry , pathology , biochemistry , gene , genetics
The incidence of human autologous transplanted skeletal myoblast (SkM) cell death in ischemic myocardium was higher in the first few days after cell therapy. We proposed that human SkM treated by human stromal cell-derived factor (SDF-1α) protein or tranfected by SDF-1α, precondition them against oxidative or anoxic injury.