Open AccessIt's easier to get along with the quiet neighbours
Author(s) -
Hurst Laurence D
Publication year - 2017
Publication title -
molecular systems biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 8.523
H-Index - 148
ISSN - 1744-4292
DOI - 10.15252/msb.20177961
Subject(s) - biology , quiet , epiphenomenon , computational biology , gene , expression (computer science) , proteomics , gene expression , rna , genetics , epistemology , computer science , philosophy , physics , quantum mechanics , programming language
Why are neighbouring genes co‐expressed at the RNA level? While it is tempting to think that this is to enable coordination of functionally related proteins, analysis of human proteomics data by Rappsilber and colleagues (Kustatscher et al , [Kustatscher G, 2017]) suggests this is the exception not the rule. Rather it might either be just something that happens or, in some instances, an epiphenomenon of coordination of expression to enable reduced gene expression noise.