Open AccessTuning noise in gene expression
Author(s) -
Tyagi Sanjay
Publication year - 2015
Publication title -
molecular systems biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 8.523
H-Index - 148
ISSN - 1744-4292
DOI - 10.15252/msb.20156210
Subject(s) - biology , chromatin , genetics , gene expression , regulation of gene expression , noise (video) , gene , promoter , expression (computer science) , computational biology , computer science , artificial intelligence , image (mathematics) , programming language
The relative contribution of promoter architecture and the associated chromatin environment in regulating gene expression noise has remained elusive. In their recent work, Arkin, Schaffer and colleagues (Dey et al , 2015) show that mean expression and noise for a given promoter at different genomic loci are uncorrelated and influenced by the local chromatin environment.