Open AccessThe riddle of the Sphinx: why sphingosine‐1‐phosphate may help define molecular mechanisms underlying risk stratification for serious COVID‐19 infections
Author(s) -
Rosen Hugh,
Oldstone Michael B A
Publication year - 2020
Publication title -
embo molecular medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.923
H-Index - 107
eISSN - 1757-4684
pISSN - 1757-4676
DOI - 10.15252/emmm.202013533
Subject(s) - sphingosine 1 phosphate , risk stratification , covid-19 , sphingosine , stratification (seeds) , pathological , biology , medicine , virology , disease , infectious disease (medical specialty) , biochemistry , receptor , outbreak , seed dormancy , botany , germination , dormancy
The sphingosine‐1‐phosphate (S1P) is a lysophospholipid signaling molecule with important functions in many physiological and pathological conditions, including viral infection. In this issue of EMBO Molecular Medicine , Marfia et al present a risk stratification based on S1P serum level as a novel prognostic indicator for COVID‐19 severity.