Open AccessLooking beyond the usual suspects: sulfide stress in schizophrenia pathophysiology
Author(s) -
Simonneau Michel
Publication year - 2019
Publication title -
embo molecular medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.923
H-Index - 107
eISSN - 1757-4684
pISSN - 1757-4676
DOI - 10.15252/emmm.201910983
Subject(s) - schizophrenia (object oriented programming) , neuroscience , pathophysiology , dopaminergic , antipsychotic , hippocampus , prefrontal cortex , psychology , psychoanalysis , psychiatry , medicine , dopamine , cognition
Schizophrenia is a complex, multifactorial disease that displays heterogeneous behavioral and cognitive syndrome (Lieberman & First, 2018). The origin of schizophrenia appears to lie in genetic and/or environmental disruption of brain development (Owen et al , 2016). In spite of current treatment that largely consists in antipsychotic drugs combined with psychological therapies, social support, and rehabilitation, developing more effective therapeutic interventions is an essential issue.
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