Open Access4 Ds in health research—working together toward rapid precision medicine
Author(s) -
Niederberger Ellen,
Parnham Michael J,
Maas Jochen,
Geisslinger Gerd
Publication year - 2019
Publication title -
embo molecular medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.923
H-Index - 107
eISSN - 1757-4684
pISSN - 1757-4676
DOI - 10.15252/emmm.201910917
Subject(s) - precision medicine , medicine , computational biology , computer science , data science , biology , pathology
Patient therapy is based mainly on a combination of diagnosis, suitable monitoring or support devices and drug treatment and is usually employed for a pre‐existing disease condition. Therapy remains predominantly symptom‐based, although it is increasingly clear that individual treatment is possible and beneficial. However, reasonable precision medicine can only be realized with the coordinated use of diagnostics, devices and drugs in combination with extensive databases (4Ds), an approach that has not yet found sufficient implementation. The practical combination of 4Ds in health care is progressing, but several obstacles still hamper their extended use in precision medicine.