Open AccessGoing viral? Linking the etiology of human prostate cancer to the PCA 3 long noncoding RNA and oncogenic viruses
Author(s) -
Teixeira Andre A,
Marchiò Serena,
DiasNeto Emmanuel,
Nunes Dia,
da Silva Israel T,
Chackerian Bryce,
Barry Marc,
Lauer Richard C,
Giordano Ricardo J,
Sidman Richard L,
Wheeler Cosette M,
Cavenee Webster K,
Pasqualini Renata,
Arap Wadih
Publication year - 2017
Publication title -
embo molecular medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.923
H-Index - 107
eISSN - 1757-4684
pISSN - 1757-4676
DOI - 10.15252/emmm.201708072
Subject(s) - prostate cancer , rna , long non coding rna , cancer , biology , non coding rna , virology , prostate , cancer research , genetics , gene
The hypothesis is discussed that prostate cancer marker lnc RNA PCA 3 was introduced into the human genome by an oncogenic virus, and that viral infection‐related mechanisms might underlie its overexpression and prostate cancer initiation and/or progression.