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Dosage compensation in human pre‐implantation embryos: X‐chromosome inactivation or dampening?
Author(s) -
Saiba Roni,
Arava Maniteja,
Gayen Srimonta
Publication year - 2018
Publication title -
embo reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.584
H-Index - 184
eISSN - 1469-3178
pISSN - 1469-221X
DOI - 10.15252/embr.201846294
Subject(s) - dosage compensation , embryo , microbiology and biotechnology , biology , chromosome , chemistry , andrology , genetics , gene , medicine
Recent studies support either X‐dampening or X‐inactivation as the mechanism of dosage compensation in human embryos. The data and possible underlying causes for these conflicting models are discussed here.