p38 links RAS to GATA 2

More than 30% of all human cancers contain activating mutations of the small G‐protein RAS . As a result of this, RAS has been intensely studied and many efforts have been made to identify pathways that sustain RAS ‐driven transformation [1][Stephen AG, 2014]. Recent studies have indicated that the transcription factor GATA 2 is one of these partners in crime, but a mechanistic link between RAS and GATA 2 had not been identified [2][Kumar MS, 2012]. A paper in this issue of EMBO reports closes this gap showing that GATA 2 can be activated by p38 in RAS‐transformed cells [3][Katsumura KR, 2014].