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Helping daughters succeed: asymmetric distribution of glucose transporter mRNA
Author(s) -
O'Donnell Allyson F,
Schmidt Martin C
Publication year - 2019
Publication title -
the embo journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.484
H-Index - 392
eISSN - 1460-2075
pISSN - 0261-4189
DOI - 10.15252/embj.2019102063
Subject(s) - biology , transporter , messenger rna , glucose transporter , genetics , distribution (mathematics) , microbiology and biotechnology , gene , endocrinology , insulin , mathematical analysis , mathematics
Rapidly proliferating cells growing by glucose fermentation must first transport glucose into the cell. Both budding yeast and human tumor cells utilize members of a conserved family of glucose transporters. In this issue of The EMBO Journal , Stahl et al (2019) reveal that budding yeast cells confer a growth advantage to their daughters using a novel mechanism, the asymmetric distribution to the daughter cell of the mRNA for a specific glucose transporter.