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STIM 1 (c) AMP s up melanogenesis
Author(s) -
Soboloff Jonathan,
Gligorijevic Bojana,
Zaidi M Raza
Publication year - 2018
Publication title -
the embo journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.484
H-Index - 392
eISSN - 1460-2075
pISSN - 0261-4189
DOI - 10.15252/embj.201899047
Subject(s) - biology , biochemistry , microbiology and biotechnology
STIM 1 and STIM 2 are endoplasmic reticulum Ca 2+ sensors that serve multi‐faceted roles in signal transduction in a wide variety of different cell types. In this issue of The EMBO Journal , Motiani et al define and characterize the ability of STIM 1 to control cAMP generation in a new context, melanin production (Motiani et al , [Motiani RK, 2018]), offering new insights into the physiological role of STIM 1.