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Dalmatian: spotting the difference in cohesin protectors
Author(s) -
Marston Adele L
Publication year - 2017
Publication title -
the embo journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.484
H-Index - 392
eISSN - 1460-2075
pISSN - 0261-4189
DOI - 10.15252/embj.201797090
Subject(s) - cohesin , biology , microbiology and biotechnology , centromere , genetics , mitosis , chromosome , gene
The cohesin complex prevents separation of chromosomes following their duplication until the appropriate time during cell division. In vertebrates, establishment and maintenance of cohesin‐dependent linkages depend on two distinct proteins, sororin and shugoshin. New findings published in The EMBO Journal show that in Drosophila , the function of both of these cohesin regulators is carried out by a single hybrid protein, Dalmatian.