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Maintaining hair follicle stem cell identity in a dish
Author(s) -
SánchezDanés Adriana,
Blanpain Cédric
Publication year - 2016
Publication title -
the embo journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.484
H-Index - 392
eISSN - 1460-2075
pISSN - 0261-4189
DOI - 10.15252/embj.201696051
Subject(s) - biology , hair follicle , stem cell , microbiology and biotechnology
Identifying and mimicking the signals that regulate stem cell self‐renewal, differentiation and maintenance in a petri dish is crucial to faithfully recapitulate stem cell behaviour in vitro . In this issue, Chacón‐Martínez et al ([Chacón‐Martínez CA, 2017]) describe novel culture conditions that allow the long‐term expansion and maintenance of functional murine hair follicle stem cells. This exciting discovery provides a faithful platform to study hair follicle stem cells in vitro and potentially perform drug screening for skin and hair follicle disorders.