Open AccessSynergistic Effects of Acoustics-based Therapy and Immunotherapy in Cancer Treatment
Author(s) -
Yuheng Bao,
Jifan Chen,
Pintong Huang,
Weijun Tong
Publication year - 2021
Publication title -
bio integration/bio integration
Language(s) - English
Resource type - Journals
eISSN - 2712-0082
pISSN - 2712-0074
DOI - 10.15212/bioi-2021-0007
Subject(s) - immunotherapy , medicine , cancer , cancer therapy , cancer treatment , cancer immunotherapy , immune system , disease , cancer research , immunology
Cancer is an intractable disease and has ability to escape immunological recognition. Cancer immunotherapy to enhance the autogenous immune response to cancer tissue is reported to be the most promising method for cancer treatment. After the release of damage-associated molecular patterns, dendritic cells come mature and then recruit activated T cells to induce immune response. To trigger the release of cancer associated antigens, cancer acoustics-based therapy has various prominent advantages and has been reported in various research. In this review, we classified the acoustics-based therapy into sonopyrolysis-, sonoporation-, and sonoluminescence-based therapy. Then, detailed mechanisms of these therapies are discussed to show the status of cancer immunotherapy induced by acoustics-based therapy in quo. Finally, we express some future prospects in this research field and make some predictions of its development direction.