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Association Between Serotonin Transporter Gene Polymorphism and Family History of Attempted and Completed Suicide
Author(s) -
Joiner Thomas E.,
Johnson Frank,
Soderstrom Ken
Publication year - 2002
Publication title -
suicide and life‐threatening behavior
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.544
H-Index - 90
eISSN - 1943-278X
pISSN - 0363-0234
DOI - 10.1521/suli.32.3.329.22167
Subject(s) - serotonin transporter , family history , polymorphism (computer science) , allele , gene polymorphism , genetics , poison control , psychology , psychiatry , gene , medicine , biology , genotype , medical emergency
The purpose of this study was to examine the association of the serotonin transporter gene to family history of suicidality. Forty‐seven volunteers responded to questionnaires about family history of suicide, and provided buccal swabs for analysis of the polymorphism. Allelic homozygocity (the short variant) was associated with family history of suicidality. These data, to be interpreted with the study's limitations in mind, suggest a link between the serotonin transporter gene polymorphism and suicide‐related variables, which should be the focus of future research.